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Zenas Files China IND for mAb to Treat Thyroid Eye Disease

publication date: May 16, 2022

Zenas BioPharma filed a China IND for Phase I/II trials of a therapy for Thyroid Eye Disease (TED). Zenas is a Shanghai-Boston biopharma that specializes in immune-based therapies. ZB001 is a differentiated humanized mAb targeting insulin-like growth factor 1 receptor (IGF-1R) for TED, a debilitating autoimmune disease that causes inflammation and fibrosis within the orbit of the eye. TED can cause double vision, pain and blindness. Zenas acquired greater China rights to ZB001 from Viridian along with other compounds targeting IGF-1R in non-oncology indications. More details....

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