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Innovent and Hanmi Start China Trials of PD-1/HER2 Bispecific

publication date: Nov 27, 2019

Suzhou Innovent Biologics started the first clinical trial of a bispecific cancer treatment that targets PD-1 and HER2. Innovent developed the bispecific, IBI315, with Beijing Hanmi Pharma, a subsidiary of Korea's Hanmi, using Hanmi's PentambodyTM bispecific platform. Although IBI315 includes a PD-1 immunotherapy, Innovent does not identify it as Tyvyt®, the company's China-approved PD-1. According to Innovent, IBI315 blocks the PD-1/PD-L1 signaling pathway, the HER2 signaling pathway, and it is also thought to bridge PD-1-expressing T cells to HER2-expressing tumor cells. More details....

Stock Symbol: (HK: 01801)

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