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ImmVira Granted US Orphan Drug Status for Oncolytic Virus Candidate in Glioma

publication date: Aug 8, 2022

Shenzhen ImmVira reported its oncolytic herpes simplex virus product MVR-C5252 was granted Orphan Drug Designation in the US to treat malignant glioma. The oHSV delivery system is designed to treat glioma by specific attenuation that promotes on-target malignant gliocyte killing while preventing off-target activity. ImmVira says MVR-C5252 is the only oncolytic virus brain tumor therapy that carries specific exogenous genes to cause an immune response in the tumor microenvironment. ImmVira’s first three oncolytic virus products are currently undergoing five Phase I/Phase II trials in the US and China. More details....

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