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Immunofoco to Start US Trial of CAR-T for Gastrointestinal Tumors

publication date: Feb 23, 2024

Shanghai Immunofoco was approved to begin a US Phase I trial of IMC001, an EpCAM-targeting autologous CAR-T cell product to treat EpCAM-positive advanced gastrointestinal tumors. The company was already approved to start China trials of the candidate. The US trial will enroll patients with advanced gastric cancer and gastroesophageal junction adenocarcinoma. EpCAM is a biomarker for circulating tumor cells, which are highly expressed in both primary and metastatic lesions of gastrointestinal tumors, while having only low expression in normal tissues. Immunofoco develops cell therapy products for solid tumors. More details....

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