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I-Mab Says CD47 Inhibitor Effective in Myelodysplastic Syndrome

publication date: Sep 12, 2022

I-Mab reported its novel CD47 inhibitor showed encouraging results in a China Phase II trial data in patients with newly diagnosed higher risk myelodysplastic syndrome (HR-MDS). Lemzoparlimab was administered in combination with azacitidine (AZA). After six months of treatment, the overall response rate was 87% and complete response rate was 40%. After four months of treatment, the efficacy was nearly as high. I-Mab, a Shanghai-Maryland biopharma, plans to conduct a randomized Phase III trial of the candidate in the same patient population. Lemzoparlimab is one of four I-Mab candidates in Phase II trials. More details....

Stock Symbol: (NSDQ: IMAB)

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