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HebaBiz Approved to Start China Trial of Novel Hepatitis B Therapy

publication date: Nov 16, 2021

Beijing HebaBiz Biotech was approved to start a China Phase III clinical study of Clevudine (L-FMAU), in patients with chronic hepatitis B virus (HBV). L-FMAU is a synthetic β-L nucleoside analogue that HebaBiz in-licensed from Yale University. The candidate binds to reverse transcriptase to inhibit HBV replication. HebaBiz says L-FMAU has a dual mechanism that provides antiviral activity while it causes a immune reaction, which it believes will sustain the suppression of the virus, giving L-FMAU the potential to be a functional cure. More details....

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