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Genor Doses First Patient in Phase I/II Trial of Bispecific for Lymphoma/Leukemia

publication date: Sep 8, 2022

Beijing Genor Biopharma dosed the first patient in a China Phase I/II clinical trial of GB261, a CD20/CD3 bispecific antibody, that will enroll lymphoma/leukemia patients. GB261 is the first T-Cell Engager with ultra-low affinity to bind CD3 and has Fc-enabled functions (ADCC and CDC). Genor says GB261 inhibits rituximab-resistant cancer cell proliferation in both in vitro assays and in vivo models with a lower level of cytokine release. The trial will enroll patients with relapsed or refractory B-cell non-Hodgkin's lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma. More details....

Stock Symbol: (HK: 6998)

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