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Cullgen Forms $1.9 Billion Collaboration with Astellas for Protein Degraders

publication date: Jun 16, 2023

Cullgen, a San Diego-Shanghai company, will collaborate with Japan's Astellas Pharma to discover multiple innovative protein degraders in a deal worth up to $1.9 billion. Cullgen will apply its proprietary uSMITE™ targeted protein degradation platform featuring novel E3 ligands with Astellas' drug discovery capabilities. Protein degraders break down proteins rather than blocking them. Initially, the two companies will focus on a cell cycle protein degrader aimed at breast cancer and other solid tumors. Cullgen will receive $35 million upfront and another $85 million if Astellas exercises an option on the lead candidate. More details....

Stock Symbol: (TSE: 4503)

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