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CARsgen and Moderna to Test Dual Claudin18.2 Cancer Therapy Combo

publication date: Aug 21, 2023

Shanghai CARsgen will collaborate with Boston’s Moderna to test a combination of their clinical stage Claudin18.2 cancer therapies in solid tumor cancers. The pairing will combine CARsgen’s CT041, an autologous Claudin18.2 CAR T-cell candidate, with Moderna’s investigational mRNA Claudin18.2 cancer vaccine. The two companies will first conduct preclinical tests and then move on to a Phase I trial. CT041 is an autologous CAR T-cell candidate that CARsgen is developing for gastric, pancreatic and other digestive system cancers in multiple ongoing clinical studies in China and North America. More details....

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