Did you know?

ChinaBio® Group is a consulting and advisory firm helping life science companies and investors achieve success in China. ChinaBio works with U.S., European and APAC companies and investors seeking partnerships, acquisitions, novel technologies and funding in China.  

Learn more >>

Free Newsletter

Have the latest stories on China's life science industry delivered to your inbox daily or weekly - free!

  Email address:

CanSino Planning Ex-China 40,000-Patient Phase III Trial of COVID-19 Vaccine

publication date: Jul 13, 2020
author/source: Richard Daverman, PhD

CanSino Biologics (HK: 6185) of Tianjin is negotiating to start Phase III trials of its COVID-19 vaccine in Russia, Brazil, Chile and/or Saudi Arabia. The trial will enroll up to 40,000 volunteers, according to Dongxu Qiu, PhD, executive director and co-founder of the company at a weekend conference in Suzhou. Dr. Qiu also said the company's vaccine produced "much higher" efficacy in its 508-person China Phase II trial than in the Phase I test, though he didn't provide specific data.

In March, CanSino's COVID-19 candidate, Ad5-nCov, was the first China vaccine to begin clinical trials. Its adenovirus-based viral vector mechanism was developed in partnership with China's Academy of Military Medicine. The two entities built the COVID-19 vaccine on their adenovirus-based Ebola developed for the 2014-16 outbreak.

China approved the use of the CanSino's vaccine for military personnel before any Phase III testing has begun.
So far, two China-developed COVID-19 vaccines, one from Sinovac Biotech and the other from a Sinopharm subsidiary, have been approved to start Phase III testing.

In May, CanSino published positive results from the China Phase I trial of its COVID-19 vaccine in the British journal, The Lancet. In the study, the vaccine was immunogenic at 28 days post-vaccination with only mild or moderate side effects.

Dr. Qiu also said that CanSino is building a manufacturing facility, which will give the company capacity to produce 100-200 million doses of the vaccine per year. The facility is expected to be ready by early next year.

See our other articles on CanSino.

Disclosure: Dr. Qiu was China General Manager of ChinaBio® from 2007 to 2012.



Share this with colleagues:


ChinaBio® News

Greg Scott BIO-Europe Interview
Greg Scott Interviewed at BIO-Europe Spring

How to bring your China assets to China in 8 minutes

Greg Scott Mendelspod Interview
"Mr. Bio in China."
Mendelspod Interview

Multinational pharma held to a higher standard in China

ChinaBio® Events

ChinaBio Partnering Forum 2020

Content Availbalble Until Dec. 21, 2020