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Alphamab and 3D Medicines File China NDA for PD-L1 Therapy

publication date: Nov 19, 2020

Alphamab Oncology and 3D Medicines filed a China NDA for their partnered anti-PD-L1 therapy as a treatment for MSI-H/dMMR cancer. In a Phase II registration trial, patients with MSI-H/dMMR colorectal cancer experienced an objective response rate of 32%. The patients had previously failed a fluoropyrimidine, oxaliplatin and irinotecan regimen. The results were roughly equivalent to those produced by BMS's Opdivo and Merck's Keytruda. In the US, Tracon Pharma partners the candidate with the two China pharmas. More details....

Stock Symbols: (HK: 9966) (NSDQ: TCON)

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