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YolTech Announces $145 Million Deal for Gene Editing Candidate

publication date: Aug 27, 2024

Shanghai’s YolTech Therapeutics sold China rights for its PCSK9-targeting base editing therapeutic to Shenzhen Salubris Pharma in a $145 million agreement. YOLT-101 is a single-course, in vivo, liver base editing medicine that is designed to permanently inhibit the PCSK9 gene in the liver to reduce disease-driving LDL-C. The candidate is currently being evaluated in several China investigator led trials. YolTech will continue preclinical development of YOLT-101, while Salubris will be responsible for clinical trials in Mainland China. YolTech will receive $30 million upfront and up to $115 million in milestones, plus tiered royalties. More details....

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