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Transcenta Cleared to Proceed in a US Phase III Trial of CLDN18.2 Antibody

publication date: Oct 4, 2023

Suzhou Transcenta was approved to start a US Phase III trial of Osemitamab, a CLDN18.2 antibody, in patients with metastatic gastric or gastroesophageal (G/GEJ) adenocarcinoma. The candidate will be administered as a first-line therapy in patients with HER2-negative, CLDN18.2 disease along with chemotherapy and/or Opdivo (nivolumab), a PD-1 drug. Transcenta says Osemitamab is a second-gen CLDN18.2 targeting antibody with improved binding affinity and enhanced cellular cytotoxicity. The US trial is part of a global Osemitamab trial being conducted by Transcenta, which has already been approved to begin the China arm. More details....

Stock Symbol: (HK: 06628)

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