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SystImmune Out-Licenses Rights for ADC to BMS in $8.4 Billion Agreement

publication date: Dec 12, 2023

SystImmune, the Seattle arm of Chengdu’s Biokin Pharma, out-licensed global rights (ex-China) for a bispecific ADC to Bristol Myers Squibb (NYSE: BMY) in a $8.4 billion agreement. SystImmune will receive $800 million upfront and up to $500 million in contingent near-term payments. The candidate, BL-B01D1, is a bispecific topoisomerase inhibitor-based ADC that targets both epidermal growth factor receptor and human epidermal growth factor receptor 3 (EGFRxHER3). It is currently in a global multi-center Phase I study for patients with metastatic or unresectable non-small cell lung cancer (NSCLC). Biokin partners SystImmune with OrbiMed, a US-China biopharma investor. More details....

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