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Simcere In-Licenses China Rights to Clinical-Stage Stroke Treatment

publication date: Nov 5, 2019

Simcere Pharma of Nanjing in-licensed greater China rights for a clinical stage drug that treats cerebral edema following stroke from Aeromics of New Haven, Connecticut. AER-271 is a first-in-class IV prodrug that delivers an inhibitor of Aquaporin-4, a water channel protein that facilitates brain swelling after ischemic strokes. It has completed an Aeromics-led Phase I trial. Aeromics will receive an upfront payment and additional development, regulatory and commercial milestones, plus tiered royalties on net sales. Simcere already markets Bicun, an edaravone free-radical scavenger to prevent strokes. More details....

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