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Mabwell’s Nectin-4 ADC Shows Efficacy in Triple-Negative Breast Cancer

publication date: May 13, 2024

Shanghai Mabwell reported positive data from a China trial of its novel Nectin-4-targeting ADC for triple-negative breast cancer. In 20 patients with advanced or metastatic disease, 50% reported an objective response and 80% experienced disease control. One patient had a complete response that has continued for 20 months so far. Mabwell says a China IND for the drug, 9MW2821, has also been accepted in combination with an immune checkpoint inhibitor. According to the company, 9MW2821 is the first the Nectin-4-targeting ADC developed by a Chinese company to start clinical trials. More details....

Stock Symbol: (SHA: 688062)

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