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Hasten Biopharma Enters $325 Million Deal for PCSK9 Cholesterol Drug

publication date: Sep 12, 2023

Shanghai Hasten Biopharma entered a $325 million agreement for greater China rights to a PCSK9 inhibitor aimed at lowering cholesterol from US-based LIB Therapeutics. Lerodalcibep is a next-gen PCSK9 inhibitor that may overcome the limitations of current low-density lipoprotein products for patients at high-risk for cardiovascular disease. In a global Phase III trial, conducted in patients with difficult-to-treat disease, lerodalcibep reduced mean LDL-C in the intent-to-treat population by 58.6% at Week 24. Hasten will make an upfront payment of $20 million to LIB and be responsible for milestones of up to $305 million. More details....

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