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CARsgen Approved to Start China Trials of Third Oncology Candidate

publication date: Dec 9, 2019

CARsgen Therapeutics, a Shanghai clinical-stage CAR-T/monoclonal antibody company, announced China approval to start clinical trials of a claudin18.2 mAb to treat advanced gastric and pancreatic adenocarcinoma. AB011 is the first humanized mAb targeting claudin18.2 to start clinical trials. Claudin18.2, a stomach-specific isoform of claudin-18, is expressed only in short-lived differentiated cells. Pathologically, it is highly expressed in gastric and pancreatic cancer, the company says. It is the third CARsgen candidate to start clinical trials. More details....

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