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BioCity Starts China Phase II Trial of ETA-Receptor Antagonist for Kidney Disease

publication date: Jun 22, 2023

BioCity Biopharma, located in Wuxi, China, will start a China Phase II trial of its novel oral endothelin A (ETA)-receptor selective antagonist, enrolling two patients with IgA nephropathy (IgAN). The multi-center study will be a randomized, placebo-controlled trial that assesses the safety and preliminary efficacy of SC0062 compared to placebo in patients suffering from chronic kidney disease with albuminuria. BioCity's Phase I trial showed a favorable safety profile in healthy subjects. The company has already started a separate Phase II trial of SC0062 for IgAN with diabetic kidney disease. More details....

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