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Ascletis Starts China Bridging Trial of FXR Agonist for Hepatitis B

publication date: Jul 14, 2021

Ascletis Pharma of Hangzhou started a China bridging trial of its FXR agonist following a successful US Phase I trial of ASC42 in healthy patients. The China trial will also enroll healthy patients in a placebo-controlled, dose escalation trial. As an FXR agonist, ASC42 inhibits the transcription of chronic hepatitis B virus. In preclinical tests, the candidate showed promise as a cure for CHB. Ascletis developed ASC42 in-house and believes it has best-in-class potential. It is also being tested as a treatment for NASH. More details....

Stock Symbol: (HK: 1672)

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