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Ascentage Pharma to Start Three Phase Ib/II Trials of Bcl2-Inhibitor

publication date: Mar 9, 2020

Suzhou Ascentage Pharma, announced approvals for three clinical studies of APG-2575, a novel Bcl-2 inhibitor, two in the US and one in China. APG-2575 is an oral drug designed to treat several hematologic malignancies by blocking Bcl-2 to restore the normal apoptosis process in cancer cells. According to Ascentage, the candidate is the first China-made Bcl-2 inhibitor to start clinical trials. In its Phase I clinical studies, APG-2575 did not exhibit any dose-limiting toxicity or tumor lysis syndrome (which is commonly associated with other Bcl-2 inhibitors). More details....

Stock Symbol: (HK: 6855)

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