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Ascentage to Begin China Phase III Trial of TKI for SDH-deficient GIST

publication date: Jun 11, 2024

Suzhou Ascentage Pharma was approved to start a China Phase III trial of olverembatinib (HQP1351) as a second-line therapy for succinate dehydrogenase (SDH)-deficient gastrointestinal stromal tumor (GIST). Olverembatinib is an orally-available novel third-generation TKI developed by Ascentage Pharma. It its latest trials, olverembatinib achieved a clinical benefit rate of 92.3% in SDH-deficient GIST patients. With a median age of diagnosis of 21 years, the disease is more common in women. It arises primarily in the gastric area with a high propensity to metastasize. More details....

Stock Symbol: (HK: 6855)

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