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AriBio Out-Licenses China Rights To Alzheimer’s Candidate in $770 Million Deal

publication date: Mar 25, 2024

South Korea’s AriBio out-licensed China rights for AR1001, an Alzheimer’s disease candidate, in an agreement worth up to $770 million ($90 million upfront). The company acquiring the asset asked to remain anonymous because of the competition for Alzheimer’s drugs in China. AR1001 is an oral PDE5 inhibitor and originally a South Korean candidate for erectile dysfunction. In pre-clinical studies, AR1001 inhibited neuron apoptosis and restored synaptic plasticity, according to the company, and it has also shown the ability to reduce hyperphosphorylated tau proteins in a Phase II trial. More details....

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