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AlphaBio Completes Trials of Therapy for NSCLC with CNS Metastases

publication date: Aug 25, 2022

Shanghai Alpha Biopharma reported the last patient visit has taken place in its Phase II/III trial of zorifertinib in patients with advanced EGFRm+ non-small cell lung cancer (NSCLC) and CNS metastases. The trial enrolled 492 patients at 55 study sites. In previous clinical and preclinical tests, zorifertinib showed high blood-brain barrier (BBB) penetration, anti-tumor activity in metastatic CNS lesions, overall efficacy in both CNS and extra-cranial diseases, and a safety profile similar to other EGFR-TKI drugs. AlphaBio acquired zorifertinib from AstraZeneca. More details....

Stock Symbol: (NYSE: AZN)

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