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Adagene Starts Global Trial of CTLA-4 Inhibitor for Solid Tumor Cancers

publication date: Mar 16, 2021

Adagene, a Suzhou-San Francisco immunotherapy company, has begun dosing patients in a global Phase I trial of ADG126 in patients with advanced solid tumors. ADG126, Adagene’s lead SAFEbody™ product candidate, is a fully-human, antagonistic mAb targeting a novel epitope of CTLA-4. The company said its SAFEbody platform is designed to limit the safety issues of anti-CTLA-4 therapies by limiting on-target off-tumor toxicities in normal tissues. Adagene developed SAFEbody using its AI-powered platform. More details...

Stock Symbol: (NSDQ: ADAG)

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