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AbelZeta Says CAR-T Shows Efficacy in Hepatocellular Carcinoma Patients

publication date: Jun 5, 2024

AbelZeta Pharma, a Maryland-Shanghai CAR-T company, reported positive results from a China Investigator-Initiated Trial of C-CAR031 in patients with heavily pretreated advanced hepatocellular carcinoma (HCC). The study showed early signs of efficacy in the patients and a manageable safety profile. C-CAR031 is an autologous, armored GPC3-targeting CAR-T therapy being developed in China, though it belongs to AstraZeneca and is based on Astra-Zeneca’s novel GPC3-targeting CAR-T platform. It is manufactured by AbelZeta in China, where it being co-developed by AbelZeta and AstraZeneca. More details....

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