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Abbisko Completes Enrollment in Global Phase III Trial for Tenosynovial Giant Cell Tumor

publication date: Apr 11, 2024

Shanghai Abbisko Therapeutics has completed patient enrollment for a pivotal global Phase III trial of pimicotinib in patients with tenosynovial giant cell tumor (TGCT). Pimicotinib is a novel, orally available small molecule inhibitor of CSF-1R. TGCT is a benign tumor that can cause painful joint swelling and stiffness. In late 2023, Abbisko sold greater China commercial rights to the drug for TGCT to Germany’s Merck in a $605 million agreement, including $70 million upfront. Merck has an option to add global rights to the candidate. The trial enrolled 94 patients at sites in China, the US and EU. More details....

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