Did you know?

ChinaBio® Group is a consulting and advisory firm helping life science companies and investors achieve success in China. ChinaBio works with U.S., European and APAC companies and investors seeking partnerships, acquisitions, novel technologies and funding in China.  

Learn more >>

Free Newsletter

Have the latest stories on China's life science industry delivered to your inbox daily or weekly - free!

See preview >>

  Email address:
   

Alphamab Starts Australian Trial of PD-L1/CTLA-4 Bispecific

publication date: Oct 10, 2018

Alphamab Oncology of Suzhou has started a Phase I clinical trial of its humanized PD-L1/CTLA-4 bispecific antibody in Australia. The company has also been approved to conduct a similar China trial of the candidate, KN046. The company said KN046 is engineered to target the tumor microenvironment, reducing side effects, while its dual target mechanism increases efficacy. In preclinical studies, KN046 showed excellent anti-tumor activity, according to Alphamab, with less toxicity than the marketed CTLA-4 antibody Yervoy. Alphamab said the Australian clinical trial also demonstrated good tolerability in humans. More details....

Share this with colleagues:


This article is available for purchase - please click here for details.

Sorry this page is available to subscribers only.
If you're not a subscriber why not subscribe today?

If you are already a subscriber, please login.

If you believe you should have received this message in error, please contact us.


 

To gain access to the members only content click here to subscribe.

You will be given immediate access to premium content on the site.

Upcoming Events

ChinaBio® Partnering Forum
September 10–11, 2024 | Shanghai, China
Register here

BIO-Europe®
November 4–6, 2024 | Stockholm, Sweden
Save €900 before September 13!
Register here

Biotech Showcase™
January 13–15, 2025 | San Francisco, CA
Save $600 before September 27!
Other Relevant Events

Antibody Engineering & Therapeutics Asia
October 21–23, 2024 | Kyoto, Japan
Save 30% with code CHINABIO30!
Register here