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Zhimeng Biopharma Out-Licenses TLR8 Agonist, an HBV Therapy, to GSK

publication date: Feb 6, 2023

Shanghai Zhimeng Biopharma signed an agreement to out-license global rights for its TLR8 agonist to GlaxoSmithKline as an HBV treatment. Zhimeng is currently conducting a US Phase I trial of CB06, and GSK will acquire the rights – including development, manufacturing and commercialization -- if the candidate posts successful results. CB06 is a potential candidate for combination with GSK’s bepirovirsen, an antisense oligonucleotide that targets all HBV messenger RNAs to decrease virus load. GSK hopes to offer a virtual cure for HBV. The financial details of the agreement were not disclosed. More details....

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