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Apollomics Starts China Phase III Trial of Leukemia Drug

publication date: Nov 22, 2021

Apollomics has dosed the first patient in a China Phase III trial of uproleselan to treat relapsed or refractory acute myeloid leukemia (AML). APL-106 is designed to block E-selectin (an adhesion molecule on cells in the bone marrow) from binding with blood cancer cells, disrupting leukemic cell resistance within the bone marrow microenvironment. In 2020, Apollomics in-licensed Greater China rights to uproleselan from GlycoMimetics in a two-drug, $189 million deal. Apollomics is headquartered in Foster City, CA with China operations in Hangzhou and Shanghai. More details....

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