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Akeso Presents Positive Trial Results from PD-1/CTLA-4 Candidate

publication date: Nov 11, 2019

Akeso Biopharma of Zhongshan presented results from an Australian Phase I trial of a novel immunotherapy, AK104, a tetrameric bispecific antibody targeting both PD-1 and CTLA-4. The trial enrolled patients with advanced solid tumors. In 25 patients, AK104 produced an overall response rate of 24% and an acceptable safety profile. The company has expanded Phase Ib/II trials of AK104 to include China and the US. Last week, Akeso announced a $150 million Series D funding to advance its portfolio of 18 mAbs. More details....

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