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CANbridge to Start China Phase II/III Trial of GBM Treatment

publication date: Apr 12, 2018

CANbridge Life Sciences of Beijing was granted China approval of an IND to start a Phase II/III trial of its lead candidate, CAN008, in patients with glioblastoma multiforme (GBM). The approval was based on a small (10 patient) Phase I trial of CAN008 in Taiwan, an example of China-Taiwan regulatory cooperation. In the Taiwan trial, CAN008 did not show any safety problems. CAN008 is a TNF-blocker that is thought to restore the immune system's anti-tumor response. Two years ago, CANbridge in-licensed greater China rights to CAN008 from Germany's Apogenix. More details....

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