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RemeGen Cleared to Start US Trials of Novel ADC for HER2 Urothelial Cancer

publication date: Apr 29, 2020

RemeGen, a Yantai biopharma, was cleared to start a US Phase II trial of its HER2 antibody drug conjugate (ADC) in patients with HER2 positive metastatic or unresectable urothelial cancer (UC). One year ago, RemeGen reported a China Phase II trial of RC48 (disitamab vedotin) produced a 51% objective response rate in the same population. Earlier this month, RemeGen closed a $100 million funding co-led by Lilly Asia Ventures and Lake Bleu Capital. The company has filed a China NDA for its lead drug, telitacicept, a fusion protein aimed at lupus. More details....

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